Cranial vault reconstruction by different materials: comparative histological study in rabbits M.F.R. Gabrielli, M.A.C. Gabrielli, E. Hochuli-Vieira, J.G. Padilha Filho, S. Saska, T. Okamoto, V.A. Pereira Filho, P.D.A. Bolini
Rev Bras Cir Traumatol Buco-Maxilo-Facial 2009: 6: 43–52
Forty adult male rabbits ( Oryctolagus cuniculus ) received, under general anaesthesia, bilateral parietal ostectomies with a 6 mm trephine bur to create full thickness critical size defects. The animals were divided into four groups, as follows:
Group I: | Bone defect filled with blood clot |
Group II: | Autogenous bone graft harvested from the contralateral side |
Group III: | High density porous polyethylene implant (Medpor) |
Group IV: | Calcium phosphate cement (Norian CRS) |