4.14
Neurologic
Antiepileptics [51]
Benzodiazepines Phenobarbital |
GABAA receptor agonist |
Carbamazepine Lacosamide Lamotrigine Phenytoin Valproic Acid Zonisamide |
Voltage‐gated sodium channels antagonist |
Ethosuximide | Calcium channel antagonist |
Levetiracetam | Binding of synaptic vesicle protein 2a [52] |
- Clinical Implications
- Continue drug perioperatively
- If discontinued, increase risk of perioperative seizure
Carbamazepine | P450 |