6.12
Liver and Biliary Disease

Viral Hepatitis

	Transmission	Acute/chronic	Symptoms
Hepatitis A	Fecal‐oral	Acute	Flu‐like Self‐limiting
Hepatitis B	Parenteral	Chronic	Can progress to cirrhosis
Hepatitis C	Parenteral	Chronic	Can progress to cirrhosis
Hepatitis D	Parental Co‐Infection with Hepatitis B	Chronic	Can progress to cirrhosis
Hepatitis E	Fecal‐oral	Acute	Flu‐like Self‐limiting ↑ Severity in pregnant women

Pathophysiology
- Inflammatory disease of liver parenchyma
- Can be acute or chronic infection depending on virus
- Hepatitis B, C, and D can lead to:
  - Cirrhosis
  - Hepatocellular carcinoma
  - Liver failure
Treatment
- Hepatitis A and E
  - Generally self‐limiting
- Hepatitis B, C, and D
  - Acute hepatitis becomes chronic after six months
  - Interferon and ribavirin
Primary Concerns
- ↓ Hepatic clearance/metabolism of anesthetics
Evaluation

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Oct 16, 2024 | Posted by mrzezo in Oral and Maxillofacial Surgery | Comments Off