6.2
Cardiac Disease
Stable Angina Pectoris
- MI/unstable angina covered in emergencies/urgencies
 - Etiology/Risk Factors
- Lifestyle/diet
 - Genetic
 - Smoking
 - Hyperlipidemia
 
 - Pathophysiology
- Imbalance of coronary O2 blood supply and demand resulting in chest pain from myocardial ischemia
- Determinants of supply
- Oxygen‐carrying capacity of blood
 - Degree of oxygen unloading from hemoglobin
 - Coronary artery blood flow (Figure 6.6)
 
 - Determinants of demand
- Heart rate
 - Afterload
 - Myocardial wall tension
 - Contractility
 
 
 - Determinants of supply
 - Stable angina should be relieved with rest and, if needed, nitroglycerin
 
 - Imbalance of coronary O2 blood supply and demand resulting in chest pain from myocardial ischemia
 - Treatment
- Lifestyle/diet modifications
 - Antiplatelets
- Aspirin
 - Clopidogrel
 
 - Nitrates, long acting
 - Nitroglycerin
 - β‐blockers
 - Calcium channel blockers
 - Revascularization
- CABG
 - PCI stent
 
 
 - Primary Concerns
- ↑ Risk of MI
 - Current antiplatelet medications
 - Previous PCI
 
 - Evaluation
- Consider cardiologist consult
 - Consider preoperative ECG
- May be normal when patient is asymptomatic
 
 - Consider echocardiogram
 - Establish DASI/METs on pages 67–68
 - History
- Provoking factors
 - Alleviating factors
 - Duration of pain discomfort
 - Last time patient had symptoms
 - Previous interventions
 
 
 - Anesthesia Management
 
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