Angiotensin‐Converting Enzyme Inhibitors

• Benazepril
• Enalapril
• Fosinopril
• Lisinopril
• Moexipril
• Perindopril
• Quinapril
• Trandolapril
• Other “‐pril” drugs
• Mechanism of Action
  • Angiotensin converting enzyme inhibitor (Figure 4.10)
• Clinical Implications
  • Consider continuing for moderate and deep sedation based on patient and surgical risk factors
  • Discontinue day of surgery for general anesthesia
  • If continued, may have increased risk of intraoperative hypotension, but an increase in perioperative cardiac events or mortality has not been demonstrated [29]
    • If epinephrine is ineffective in managing hypotension, consider vasopressin
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