Acellular dermal regenerative matrix material “Integra™” as an adjunct for radial forearm free flap donor site closure

Having read with interest the recent review by Pabst et al, we would like to add the acellular dermal matrix material “Integra™” to the exhaustive list they have extensively reviewed. We noted that they had excluded any case series of fewer than five patients.

A series by Murray et al described its use followed by an ultrathin skin graft for closing the donor site. Adams et al showed its use in treating a variety of wounds in the extremities.

We have used Integra™ to minimise the donor site scarring to treat a fit and healthy right-handed 37-year-old man who presented with a mucoepidermoid carcinoma arising from minor salivary glands in the hard palate. He required resection and reconstruction with a left radial forearm free flap. He had Type 1 Fitzpatrick skin, was prone to severe keloid scarring, and was not keen to have a skin graft that would cause further scars.

This material provides a dermal substrate consisting of denatured bovine collagen and shark chondroitin sulphate. It is available as either a monolayer construct or as a bilayer construct with a silastic outer portion. Two weeks after the arm dressing was removed, the Integra™ bilayer is shown in our patient ( Fig. 1 ).

Aug 5, 2020 | Posted by in Oral and Maxillofacial Surgery | Comments Off on Acellular dermal regenerative matrix material “Integra™” as an adjunct for radial forearm free flap donor site closure
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