3 Investigations: Histopathology
Box 3.1 Indications for biopsy
Indications for biopsy include lesions that:
- have neoplastic or potentially malignant features
- are enlarging
- persist > 3 weeks
- are of uncertain etiology
- fail to respond to treatment
- cause concern.
Having taken a careful history and completed the clinical examination, the clinician is often in a position to formulate the diagnosis, or at least a list of differential diagnoses. In the la/>