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pandora rings A second order loop would involve two other interventions (such as A v C, C v D, and D v B; see green and blue dashed lines in fig 2). Higher order loops involve additional interventionsIntransitivity Differences in study characteristics that may modify treatment effect in the direct comparisons (such as A v C and B v C) that form the basis for the indirect estimate of effect of the comparison of interest (A v B), and thus bias the indirect assessment of A versus B. Factors that may modify treatment effects include differing patient characteristics; differing co interventions; differing extent to which interventions of interest are optimally administered; differing comparators; and differences in measurement of outcomeHeterogeneity Differences in estimates of effect across studies that assessed the same comparisonRationale for an approach to rate the quality of evidence from NMARecently, several articles have provided guidance regarding identification of the evidence for a NMA,9 statistical aspects of conducting NMA,10 11 12 13 14 15 16 17 and critical appraisal and interpretation of published NMA.18 19 Few of these, however, provide explicit guidance on how to rate the quality of the evidence.4 20 21Reports of NMAs often describe the risk of bias of trials included in a NMA (such as method of randomisation, concealment of random allocation, masking https://www.jewelleryflq679.top, etc).22 23 24 For example, a recent NMA compared the effects of coronary artery bypass grafting, various stents, and medical treatment on mortality, myocardial infarction, and the need for revascularisation among patients with stable coronary artery disease pandora rings.

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